The natural compound caffeic acid phenethyl ester (CAPE) found in Bio 30 propolis is the main cancer-suppressing ingredient.

Bio 30 propolis has high levels of CAPE. A 2006 study found the CAPE content of New Zealand propolis was many times higher than propolis from other countries.

Since its identification as the main cytotoxic compound in propolis, CAPE has become the most studied of all the individual constituents of propolis.

In an article in the International Bee Research Association’s Journal of ApiProduct and ApiMedical Science, Bulgarian researcher Vassya Bankova describes CAPE as “the ultimate success story of a bioactive compound isolated from propolis”.

“It was found to induce apoptosis (rapid cell death) of human pancreatic cancer cells and colon cancer cells. It inhibited the growth of C6 glioma cells in vitro and in vivo. Other studies prove its chemopreventive effect.”

“CAPE has been proven to block the process involved in the enhanced growth seen in several cancers.

“Dietary intake of safe and nontoxic chemopreventives like CAPE may thus be beneficial for patients whose tumours express persistently high levels of activated NF-κB, such as non-small cell lung carcinoma, thyroid, colon, breast, stomach, squamous head and neck carcinomas.

“Recently, CAPE was considered a promising substance for anti-HIV therapy as it was found to be an effective inhibitor of HIV-1 integrase.”

CAPE blocks the formation of tumors by down-regulating the PAK gene. PAK is an enzyme essential for a number of physiological functions such as cell growth and migration, blood vessel function and memory/learning.

The human body normally has a very sophisticated mechanism to maintain a balance (homeostasis) of each element essential for good health. However, genetic disorders and environmental stresses break down this balance, leading to either deficiency or over-production of certain elements, resulting in severe illness.

PAK-dependent cancers require the kinase PAK1 for their growth. CAPE-based Bio 30 propolis extract completely suppresses the growth of tumors invivo by blocking PAK1 signaling. The CAPE in Bio 30 propolis works synergistically with other anti-cancer compounds including galangin, chrysin, caffeic acid and apigenin.

The following cancers are either 100% dependent on the PAK1 pathway or on other contributing mechanisms that affect the PAK1 pathway:

  • Pancreatic cancer
  • Melanoma and gliomas
  • Multiple myeloma
  • Breast cancer
  • Prostrate cancer
  • Colon cancer
  • Cervical cancer
  • Ovarian cancer
  • NF (neurofibromatosis)
  • Other severe illnesses caused by the PAK1 enzyme:
  • Mental retardation or learning deficit (LD)
  • Fragile X-syndrome (autism)
  • Inflammation (asthma and arthritis)
  • Epilepsy
  • Hyper-tension
  • AD (Alzheimer’s Disease)
  • HD (Huntington’s Disease)

To cure or treat these illnesses, the PAK level has to be reduced to a bare minimum.